BDBM50546246 CHEMBL4753043::US11608319, Compound AR-13503
SMILES NC[C@@H](C(=O)Nc1ccc2cnccc2c1)c1ccc(CO)cc1
InChI Key InChIKey=LTXBFJFJUIJOQE-GOSISDBHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50546246
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Taipei Medical University
Curated by ChEMBL
Taipei Medical University
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Inhibition of human ROCK2 expressed in baculovirus expression system by Kinase-Glo luminescent AssayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Taipei Medical University
Curated by ChEMBL
Taipei Medical University
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Inhibition of human ROCK1 expressed in baculovirus expression system by Kinase-Glo luminescent AssayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Taipei Medical University
Curated by ChEMBL
Taipei Medical University
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Inhibition of recombinant human GST-tagged ROCK2 catalytic domain expressed in baculovirus expression system by Kinase-Glo luminescent kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Taipei Medical University
Curated by ChEMBL
Taipei Medical University
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Inhibition of recombinant human GST-tagged ROCK1 catalytic domain expressed in baculovirus expression system by Kinase-Glo luminescent kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Taipei Medical University
Curated by ChEMBL
Taipei Medical University
Curated by ChEMBL
Affinity DataIC50: <1nMAssay Description:Table 2: Inhibitory effect of each compound synthesized above on Rho-associated protein kinase (ROCK) was tested.Method 1. 10 mM test compound was di...More data for this Ligand-Target Pair
TargetMyosin light chain kinase family member 4(Homo sapiens (Human))
Industrial Technology Research Institute
US Patent
Industrial Technology Research Institute
US Patent
Affinity DataIC50: 550nMAssay Description:Table 4: Assay for Inhibitory Effect on Myosin Light Chain Kinase 4 (MYLK-4). The experimental procedure referred to the LanthaScreen Eu Kinase Bindi...More data for this Ligand-Target Pair