BDBM505531 (3aR,6aR)-5-cyano-N-(4- (trifluoromethyl)-phenyl)- hexahydropyrrolo[3,4-b] pyrrole-1(2H)-carboxamide::US11066365, Example 203::US11390584, Example 203

SMILES FC(F)(F)c1ccc(NC(=O)N2CC[C@@H]3CN(C[C@H]23)C#N)cc1

InChI Key InChIKey=DOIDLBGKYGDVFZ-MFKMUULPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 505531   

TargetUbiquitin carboxyl-terminal hydrolase 30(Homo sapiens (Human))
Mission Therapeutics

US Patent
LigandPNGBDBM505531((3aR,6aR)-5-cyano-N-(4- (trifluoromethyl)-phenyl)-...)
Affinity DataIC50: <100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30(Homo sapiens (Human))
Mission Therapeutics

US Patent
LigandPNGBDBM505531((3aR,6aR)-5-cyano-N-(4- (trifluoromethyl)-phenyl)-...)
Affinity DataIC50: <100nMAssay Description:USP30 biochemical fluorescence intensity IC50 assay Dilution plates were prepared at 21 times the final concentration (2100 μM for a final conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent