BDBM50554034 CHEMBL4747269

SMILES Nc1cc([C@H](CCN[C@H]2C[C@H](c3ccccc23)c2ccccc2)c2ccccc2)c2nn[nH]c2n1

InChI Key

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50554034   

TargetMyeloperoxidase(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50554034(CHEMBL4747269)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of PMA-induced MPO in human Neutrophil incubated for 3 mins by luminometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetEosinophil peroxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50554034(CHEMBL4747269)
Affinity DataIC50:  92nMAssay Description:Inhibition of human EPX bromination activity using tyrosine as substrate by measuring 3-bromo tyrosine formation incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetLactoperoxidase(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50554034(CHEMBL4747269)
Affinity DataIC50: >6.20E+4nMAssay Description:Inhibition of LPO (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetMyeloperoxidase(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50554034(CHEMBL4747269)
Affinity DataIC50:  1nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB