BDBM50559449 CHEMBL4779950
SMILES CC(C)c1noc(n1)N1CCC(CC1)Oc1cc(ncn1)N1CCc2cc(ccc12)N1CCC[C@H](O)C1=O
InChI Key InChIKey=WYCBJYYEIKRIBR-QFIPXVFZSA-N
Data 5 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50559449
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataEC50: 120nMAssay Description:Agonist activity at rat GPR119 expressed in CHO cells co-expressing cyclic AMP response element incubated for 2 hrs by steady-glo luciferase assayMore data for this Ligand-Target Pair
Affinity DataEC50: 19nMAssay Description:Agonist activity at GPR119 in glucose-induced mouse L cells assessed as induction of GLP-1 secretion after 2 hrs by ELISAMore data for this Ligand-Target Pair
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataEC50: 16nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element-luciferase reporter gene incubated for 2 hrs by ste...More data for this Ligand-Target Pair
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataEC50: 16nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element incubated for 2 hrs by steady-glo luciferase assayMore data for this Ligand-Target Pair
Targetglucose-dependent insulinotropic receptor(Mesocricetus auratus)
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataEC50: 25nMAssay Description:Agonist activity at GPR119 in glucose-induced golden hamster HIT-T15 cells assessed as increase in insulin secretion after 2 hrs by A1phaLISAMore data for this Ligand-Target Pair