BDBM50559449 CHEMBL4779950

SMILES CC(C)c1noc(n1)N1CCC(CC1)Oc1cc(ncn1)N1CCc2cc(ccc12)N1CCC[C@H](O)C1=O

InChI Key InChIKey=WYCBJYYEIKRIBR-QFIPXVFZSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50559449   

TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559449(CHEMBL4779950)
Affinity DataEC50:  120nMAssay Description:Agonist activity at rat GPR119 expressed in CHO cells co-expressing cyclic AMP response element incubated for 2 hrs by steady-glo luciferase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559449(CHEMBL4779950)
Affinity DataEC50:  19nMAssay Description:Agonist activity at GPR119 in glucose-induced mouse L cells assessed as induction of GLP-1 secretion after 2 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559449(CHEMBL4779950)
Affinity DataEC50:  16nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element-luciferase reporter gene incubated for 2 hrs by ste...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559449(CHEMBL4779950)
Affinity DataEC50:  16nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element incubated for 2 hrs by steady-glo luciferase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Targetglucose-dependent insulinotropic receptor(Mesocricetus auratus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559449(CHEMBL4779950)
Affinity DataEC50:  25nMAssay Description:Agonist activity at GPR119 in glucose-induced golden hamster HIT-T15 cells assessed as increase in insulin secretion after 2 hrs by A1phaLISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed