BDBM50559821 CHEMBL4781596

SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)cc2)c(F)c1

InChI Key InChIKey=OQDKZJYHCUFKRI-LRDDRELGSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50559821   

TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559821(CHEMBL4781596)
Affinity DataEC50:  0.140nMAssay Description:Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559821(CHEMBL4781596)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of recombinant human CYP3A4More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFormyl peptide receptor 2(Mus musculus)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559821(CHEMBL4781596)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at mouse FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559821(CHEMBL4781596)
Affinity DataEC50:  280nMAssay Description:Agonist activity at human FPR1 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed