BDBM50561741 CHEMBL4777759

SMILES C[C@@H]1CN(CCO1)c1cccc(NC(=O)c2ccc(cc2N2CCC3(CC3)CC2)S(=O)(=O)NCCO)n1

InChI Key InChIKey=JWRMZCHFPHKPAS-LJQANCHMSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50561741   

TargetKinesin-like protein KIF18A(Homo sapiens)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50561741(CHEMBL4777759)
Affinity DataIC50:  16nMAssay Description:Inhibition of recombinant human His-tagged KIF18A (1 to 467 residues) expressed in baculovirus expression system assessed as inhibition of microtubul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed