BDBM50562972 CHEMBL4799997
SMILES NS(=O)(=O)c1ccc(cc1)N1CCN(C1=O)c1ccc(F)cc1F
InChI Key InChIKey=SGCKOJXZNTVQLM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 19 hits for monomerid = 50562972
Affinity DataKi: 0.25nMAssay Description:Inhibition of human CAH7 expressed in Escherichia coli BL21 (DE3) by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.40nMAssay Description:Inhibition of CAH9 in human T47D cells under normoxic condition by membrane inlet for mass spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Inhibition of human CAH12 expressed in Escherichia coli BL21 (DE3) by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.10nMAssay Description:Inhibition of CAH9 in human MCF-10A cells under hypoxic condition by membrane inlet for mass spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of human CAH6 expressed in Escherichia coli BL21 (DE3) by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Inhibition of human CAH2 expressed in Escherichia coli BL21 (DE3) by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Inhibition of human CAH13 expressed in Escherichia coli BL21 (DE3) by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Inhibition of CAH9 in human UFH-001 cells under hypoxic condition by membrane inlet for mass spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Inhibition of human CAH9 catalytic domain expressed in Escherichia coli BL21 (DE3) by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Inhibition of human CAH14 expressed in Escherichia coli BL21 (DE3) by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 49nMAssay Description:Inhibition of CAH9 in human UFH-001 cells under normoxic condition by membrane inlet for mass spectrometryMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
University Of Florida
Curated by ChEMBL
University Of Florida
Curated by ChEMBL
Affinity DataKi: 54nMAssay Description:Inhibition of human CAH5B expressed in Escherichia coli BL21 (DE3) by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
University Of Florida
Curated by ChEMBL
University Of Florida
Curated by ChEMBL
Affinity DataKi: 63nMAssay Description:Inhibition of human CAH5A expressed in Escherichia coli BL21 (DE3) by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of human CAH4 expressed in Escherichia coli BL21 (DE3) by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:Inhibition of human CAH1 expressed in Escherichia coli BL21 (DE3) by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.20E+3nMAssay Description:Inhibition of CAH9 in human T47D cells under hypoxic condition by membrane inlet for mass spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human CAH3 expressed in Escherichia coli BL21 (DE3) by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of human CAH9 catalytic domain expressed in Escherichia coli BL21 (DE3) assessed as reduction in esterase activity using p-nitrophenyl ace...More data for this Ligand-Target Pair
Affinity DataIC50: 780nMAssay Description:Inhibition of human full length CAH2 expressed in Escherichia coli BL21 (DE3) assessed as reduction in esterase activity using p-nitrophenyl acetate ...More data for this Ligand-Target Pair