BDBM505786 (S)-6-((benzo[d]thiazol-7-yl(1-(1- methylcyclopropyl)-1H-1,2,3-triazol-4- yl)methyl)am ino)-4-(neopentylamino)- quinoline-3,8-dicarbonitrile::US11066414, Compound 435

SMILES CC(C)(C)CNc1c(cnc2c(cc(N[C@H](C3=CN(NN3)C3(C)CC3)c3cccc4ncsc34)cc12)C#N)C#N

InChI Key InChIKey=JKJDSDBANYSFOG-MHZLTWQESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 505786   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM505786((S)-6-((benzo[d]thiazol-7-yl(1-(1- methylcycloprop...)
Affinity DataIC50:  1nMAssay Description:EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent