BDBM506368 US11045448, Cpd. No. 77::methyl ((1S,2R)-2-((1S)-(1-((1-(4-((1-acryloylpyrrolidin-3- yl)sulfonyl)phenyl)azetidin-3-yl)methyl)piperidin-4- yl)(cyano)(3-fluorophenyl)methyl)cyclopentyl)carbamate
SMILES COC(=O)N[C@H]1CCC[C@@H]1[C@@](C#N)(C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)C2CCN(C2)C(=O)C=C)CC1)c1cccc(F)c1
InChI Key InChIKey=SZPVXYFJAKCTNY-KVDTUNPMSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 506368
Affinity DataIC50: 11nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair