BDBM506372 2-chloro-N-((1S,2R)-2-((S)-cyano(1-((1-(4-cyanophenyl)azetidin-3- yl)methyl)piperidin-4-yl)(3- fluorophenyl)methyl)cyclopentyl)acetamide::US11045448, Cpd. No. 81

SMILES Fc1cccc(c1)[C@@](C#N)([C@H]1CCC[C@@H]1NC(=O)CCl)C1CCN(CC2CN(C2)c2ccc(cc2)C#N)CC1

InChI Key InChIKey=DVNFEYRAKDFYTF-QMOZSOIISA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 506372   

TargetMenin(Homo sapiens (Human))
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US Patent
LigandPNGBDBM506372(2-chloro-N-((1S,2R)-2-((S)-cyano(1-((1-(4-cyanophe...)
Affinity DataIC50:  9nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent