BDBM506550 US11045457, Example 150

SMILES CN1C[C@H](NC(=O)C(C)(C)COc2ncccc2OC(F)(F)F)C2(CC2)C1

InChI Key InChIKey=MLRFRFMLBSEBMO-ZDUSSCGKSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 506550   

TargetSomatostatin receptor type 4(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM506550(US11045457, Example 150)
Affinity DataEC50:  6.31nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM506550(US11045457, Example 150)
Affinity DataIC50:  2.51E+3nMAssay Description:This membrane-based assay measures the ability of compounds to competitively inhibit binding of I-125 labeled somatostatin to SSTR1 in membranes from...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM506550(US11045457, Example 150)
Affinity DataIC50:  50.1nMAssay Description:This membrane-based assay measures the ability of compounds to competitively inhibit binding of I-125 labeled somatostatin to SSTR4 in membranes from...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent