BDBM506744 N-(5-chloropyridin-2-yl)-2- cyclopropyl-2- ((1R,3s,5S,6r)-3-((6- fluoroquinolin-4-yl)- oxy)bicyclo[3.1.0]hexan-6- yl)acetamide::US11046649, Ex. 122

SMILES Fc1ccc2nccc(O[C@H]3C[C@H]4[C@@H](C3)[C@@H]4C(C3CC3)C(=O)Nc3ccc(Cl)cn3)c2c1

InChI Key InChIKey=BCVGRUVHJQQLOJ-WEGQQRCMSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 506744   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM506744(N-(5-chloropyridin-2-yl)-2- cyclopropyl-2- ((1R,3s...)
Affinity DataIC50:  4nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent