BDBM506747 2-cyclopropyl-2- ((1R,3s,5S,6r)-3-((6- fluoroquinolin-4- yl)oxy)bicyclo[3.1.0]- hexan-6-yl)-N-(1- (trifluoromethyl)-1H- pyrazol-3-yl)acetamide::US11046649, Ex. 125

SMILES Fc1ccc2nccc(O[C@H]3C[C@H]4[C@@H](C3)[C@@H]4C(C3CC3)C(=O)Nc3ccn(n3)C(F)(F)F)c2c1

InChI Key InChIKey=XUMSITWXFJJEKH-KKUXPYBFSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 506747   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM506747(2-cyclopropyl-2- ((1R,3s,5S,6r)-3-((6- fluoroquino...)
Affinity DataIC50:  2.02nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent