BDBM506756 5,6-Difluoro-1- ((1R,3s,5S,6r)-6-(1-(5- (trifluoromethyl)-1H- benzo[d]imidazol-2-yl)- ethyl)bicyclo[3.1.0]hexan- 3-yl)-1H- benzo[d]imidazole::US11046649, Ex. 134

SMILES CC([C@@H]1[C@H]2C[C@@H](C[C@@H]12)n1cnc2cc(F)c(F)cc12)c1nc2cc(ccc2[nH]1)C(F)(F)F

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 506756   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM506756(5,6-Difluoro-1- ((1R,3s,5S,6r)-6-(1-(5- (trifluoro...)
Affinity DataIC50:  10.6nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent