BDBM506786 US11046651, Compound 8

SMILES CC(C)(CN1CCN(CC1)C1=Nc2ccccc2Cc2ccccc12)C(O)=O

InChI Key InChIKey=DMYWKEKMOKMLKU-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 506786   

TargetHistamine H1 receptor(Homo sapiens (Human))
Alairion

US Patent
LigandPNGBDBM506786(US11046651, Compound 8)
Affinity DataKi:  37.5nMAssay Description:1 μl of a compounds of the present disclosure and either reference compound (Table C) were transferred to assay plates. 1 μl of 0.2 mM Keta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H1 receptor(Homo sapiens (Human))
Alairion

US Patent
LigandPNGBDBM506786(US11046651, Compound 8)
Affinity DataKi:  46nMAssay Description:1 μl of a compounds of the present disclosure and either reference compound (Table C) were transferred to assay plates. 1 μl of 0.2 mM Keta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Alairion

US Patent
LigandPNGBDBM506786(US11046651, Compound 8)
Affinity DataKi: >50nMAssay Description:1 μL of a compound of the present disclosure the reference compound (Table J) was transferred to an assay plate. 1 μL of 0.2 mM SB-206533 w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Alairion

US Patent
LigandPNGBDBM506786(US11046651, Compound 8)
Affinity DataKi: >50nMAssay Description:1 μl of a compounds of the present disclosure and either reference compound (Table C) were transferred to assay plates. 1 μl of 0.2 mM Keta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Alairion

US Patent
LigandPNGBDBM506786(US11046651, Compound 8)
Affinity DataKi:  87nMAssay Description:1 μl of a compounds of the present disclosure and either reference compound (Table C) were transferred to assay plates. 1 μl of 0.2 mM Keta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent