BDBM506888 3-amino-6-(5-(3-amino-1,1,1-trifluoro-2-hydroxy-3-oxopropan-2-yl)-2-methylphenyl)-N-(3,3,3-trifluoro-2-hydroxypropyl)pyrazine-2-carboxamide::US11046658, Example 43A::US11046658, Example 43B++

SMILES Cc1ccc(cc1-c1cnc(N)c(n1)C(=O)NCC(O)C(F)(F)F)C(O)(C(N)=O)C(F)(F)F

InChI Key InChIKey=WFPRGQZILLAXQE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 506888   

LigandPNGBDBM506888(3-amino-6-(5-(3-amino-1,1,1-trifluoro-2-hydroxy-3-...)
Affinity DataIC50: <100nMAssay Description:Materials: [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin Elmer (Waltham, Mass.). ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM506888(3-amino-6-(5-(3-amino-1,1,1-trifluoro-2-hydroxy-3-...)
Affinity DataIC50: <100nMAssay Description:Materials: [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin Elmer (Waltham, Mass.). ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM506888(3-amino-6-(5-(3-amino-1,1,1-trifluoro-2-hydroxy-3-...)
Affinity DataIC50: <100nMAssay Description:Materials: [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin Elmer (Waltham, Mass.). ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM506888(3-amino-6-(5-(3-amino-1,1,1-trifluoro-2-hydroxy-3-...)
Affinity DataIC50: <100nMAssay Description:Materials: [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin Elmer (Waltham, Mass.). ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent