BDBM506900 2-(3-(5-amino-6-((1-methyl- 1H-pyrazol-4- yl)ethynyl)pyrazin-2-yl)-4- methylphenyl)-3,3,3-trifluoro- 2-hydroxypropanamide::US11046658, Example 54

SMILES Cc1ccc(cc1-c1cnc(N)c(n1)C#Cc1cnn(C)c1)C(O)(C(N)=O)C(F)(F)F

InChI Key InChIKey=YLCPYBKXGQBIOB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 506900   

LigandPNGBDBM506900(2-(3-(5-amino-6-((1-methyl- 1H-pyrazol-4- yl)ethyn...)
Affinity DataIC50: <100nMAssay Description:Materials: [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin Elmer (Waltham, Mass.). ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM506900(2-(3-(5-amino-6-((1-methyl- 1H-pyrazol-4- yl)ethyn...)
Affinity DataIC50: <100nMAssay Description:Materials: [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin Elmer (Waltham, Mass.). ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent