BDBM506922 2-(3-(5-amino-6-(1-(2- cyanopropan-2-yl)-1H- pyrazol-4-yl)pyrazin-2-yl)- 4-methylphenyl)-3,3,3- trifluoro-2- hydroxypropanamide trifluoroacetate::US11046658, Example 76
SMILES Cc1ccc(cc1-c1cnc(N)c(n1)-c1cnn(c1)C(C)(C)C#N)C(O)(C(N)=O)C(F)(F)F
InChI Key InChIKey=WHCDEJXBJNMIBB-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 506922
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Incyte
US Patent
Incyte
US Patent
Affinity DataIC50: <100nMAssay Description:Materials: [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin Elmer (Waltham, Mass.). ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Incyte
US Patent
Incyte
US Patent
Affinity DataIC50: <100nMAssay Description:Materials: [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin Elmer (Waltham, Mass.). ...More data for this Ligand-Target Pair