BDBM506976 Sodium 2-(3-fluorophenyl)-5- propanoyl-1,3-thiazol-4-olate::US11046662, Compound 2

SMILES CCC(=O)c1sc(nc1[O-])-c1cccc(F)c1

InChI Key InChIKey=ANUOYWLYYBOAMH-UHFFFAOYSA-M

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 506976   

TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
DompÉ

US Patent
LigandPNGBDBM506976(Sodium 2-(3-fluorophenyl)-5- propanoyl-1,3-thiazol...)
Affinity DataIC50: >1.00E+4nMAssay Description:In order to address more specifically the potential selectivity issues, a counterassay was carried out for compound 2 against TRPV1 and TRPV4 ion cha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
DompÉ

US Patent
LigandPNGBDBM506976(Sodium 2-(3-fluorophenyl)-5- propanoyl-1,3-thiazol...)
Affinity DataIC50:  28nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
DompÉ

US Patent
LigandPNGBDBM506976(Sodium 2-(3-fluorophenyl)-5- propanoyl-1,3-thiazol...)
Affinity DataIC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
DompÉ

US Patent
LigandPNGBDBM506976(Sodium 2-(3-fluorophenyl)-5- propanoyl-1,3-thiazol...)
Affinity DataIC50: >1.00E+4nMAssay Description:a. Cloning, Sequencing, Transfection and Selection of Positive Clones Expressing Human TRPM8A functional cell-based assay for the identification of T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent