BDBM507693 7-(5-(5-(4- acetylpiperazine-1- carbonyl)-1,3,4- thiadiazol-2-yl)-4- (isopropylamino)pyridin- 2-yl)pyrrolo[1,2- b]pyridazine-3- carbonitrile::US11046686, Example 10::US11702414, Example 10

SMILES CC(C)Nc1cc(ncc1-c1nnc(s1)C(=O)N1CCN(CC1)C(C)=O)-c1ccc2cc(cnn12)C#N

InChI Key InChIKey=SGFLRPLWBHLYGN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 507693   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM507693(7-(5-(5-(4- acetylpiperazine-1- carbonyl)-1,3,4- t...)
Affinity DataIC50: <1nMAssay Description:IRAK4 enzyme (Carna Biosciences, Chuo-ku, Kobe, Japan) activity was measured by detecting phosphorylated peptide substrate formation using an antibod...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM507693(7-(5-(5-(4- acetylpiperazine-1- carbonyl)-1,3,4- t...)
Affinity DataIC50: <1nMAssay Description:IRAK4 enzyme (Carna Biosciences, Chuo-ku, Kobe, Japan) activity was measured by detecting phosphorylated peptide substrate formation using an antibod...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent