BDBM507701 7-(4-(isopropylamino)- 5-(5-(morpholine-4- carbonyl)-1,3,4- thiadiazol-2-yl)pyridin- 2-yl)pyrrolo[1,2- b]pyridazine-3- carbonitrile::US11046686, Example 18::US11702414, Example 18

SMILES CC(C)Nc1cc(ncc1-c1nnc(s1)C(=O)N1CCOCC1)-c1ccc2cc(cnn12)C#N

InChI Key InChIKey=ZXBVAQXEHOZBBJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 507701   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM507701(7-(4-(isopropylamino)- 5-(5-(morpholine-4- carbony...)
Affinity DataIC50:  1.00E+3nMAssay Description:IRAK4 enzyme (Carna Biosciences, Chuo-ku, Kobe, Japan) activity was measured by detecting phosphorylated peptide substrate formation using an antibod...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM507701(7-(4-(isopropylamino)- 5-(5-(morpholine-4- carbony...)
Affinity DataIC50:  1.00E+3nMAssay Description:IRAK4 enzyme (Carna Biosciences, Chuo-ku, Kobe, Japan) activity was measured by detecting phosphorylated peptide substrate formation using an antibod...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent