BDBM507703 N-((1r,4r)-4-(5-(4- ((cyanomethyl)amino)- 6-(3-cyanopyrrolo[1,2- b]pyridazin-7- yl)pyridin-3-yl)-1,3,4- thiadiazol-2- yl)cyclohexyl)acetamide::US11046686, Example 20

SMILES CC(=O)NC1CC[C@@H](CC1)c1nnc(s1)-c1cnc(cc1NCC#N)-c1ccc2cc(cnn12)C#N

InChI Key InChIKey=AGZHXRVAZPHSTC-FNGKDXACSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 507703   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM507703(N-((1r,4r)-4-(5-(4- ((cyanomethyl)amino)- 6-(3-cya...)
Affinity DataIC50: <1nMAssay Description:IRAK4 enzyme (Carna Biosciences, Chuo-ku, Kobe, Japan) activity was measured by detecting phosphorylated peptide substrate formation using an antibod...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent