BDBM507709 7-(5-(5-(2-aminoethyl)-1,3,4-thiadiazol-2-yl)-4-(isopropylamino)pyridin-2-yl)pyrrolo[1,2-b]pyridazine-3-carbonitrile(Example 26)::US11046686, Example 26::US11702414, Example 212::US11702414, Example 26

SMILES CC(C)Nc1cc(ncc1-c1nnc(CCN)s1)-c1ccc2cc(cnn12)C#N

InChI Key InChIKey=RDHCSBXWDQZMOG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 507709   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM507709(7-(5-(5-(2-aminoethyl)-1,3,4-thiadiazol-2-yl)-4-(i...)
Affinity DataIC50:  1nMAssay Description:IRAK4 enzyme (Carna Biosciences, Chuo-ku, Kobe, Japan) activity was measured by detecting phosphorylated peptide substrate formation using an antibod...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM507709(7-(5-(5-(2-aminoethyl)-1,3,4-thiadiazol-2-yl)-4-(i...)
Affinity DataIC50:  1.01E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM507709(7-(5-(5-(2-aminoethyl)-1,3,4-thiadiazol-2-yl)-4-(i...)
Affinity DataIC50:  1nMAssay Description:IRAK4 enzyme (Carna Biosciences, Chuo-ku, Kobe, Japan) activity was measured by detecting phosphorylated peptide substrate formation using an antibod...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent