BDBM508 2-[(2,4-dichlorophenyl)(3-hydroxy-1,4-dioxo-1,4-dihydronaphthalen-2-yl)methyl]-3-hydroxy-1,4-dihydronaphthalene-1,4-dione::CHEMBL291663::Cancer Chemotherapy National Service Center (CCNSC) compound 117272::NSC 117272

SMILES Oc1c(O)c2ccccc2c(O)c1C(=C1C(=O)C(=O)c2ccccc2C1=O)c1ccc(Cl)cc1Cl

InChI Key InChIKey=GTKAWFLUACSQAN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 508   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes Of Health

LigandPNGBDBM508(2-[(2,4-dichlorophenyl)(3-hydroxy-1,4-dioxo-1,4-di...)
Affinity DataIC50:  2.40E+4nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM508(2-[(2,4-dichlorophenyl)(3-hydroxy-1,4-dioxo-1,4-di...)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibitory activity against HIV-1 integraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM508(2-[(2,4-dichlorophenyl)(3-hydroxy-1,4-dioxo-1,4-di...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM508(2-[(2,4-dichlorophenyl)(3-hydroxy-1,4-dioxo-1,4-di...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibitory activity against HIV-1 integraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed