BDBM508546 2,2-difluoro-8-{2-[3-fluoro-3- (trifluoromethyl)azetidin-1- yl]ethyl}[1,3]dioxolo[4,5- h][1,2,4]triazolo[1,5- c]quinazolin-5-amine::US11046714, Example 21

SMILES Nc1nc2c3OC(F)(F)Oc3ccc2c2nc(CCN3CC(F)(C3)C(F)(F)F)nn12

InChI Key InChIKey=ONMYIBRCVRGHAC-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 508546   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM508546(2,2-difluoro-8-{2-[3-fluoro-3- (trifluoromethyl)az...)
Affinity DataKi:  3.40nMAssay Description:The following table shows representative data for the compounds of the Examples as A2a receptor antagonists as determined by a competition binding as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent