BDBM508600 2,2-difluoro-8-{2-[(4aR,7aR)- octahydro-6H-pyrrolo[3,4-b] pyridin-6-yl]ethyl}[1,3]dioxolo [4,5-h][1,2,4]triazolo[1,5- c]quinazolin-5-amine::US11046714, Example 51

SMILES Nc1nc2c3OC(F)(F)Oc3ccc2c2nc(CCN3C[C@H]4CCCN[C@H]4C3)nn12

InChI Key InChIKey=XMYHFGZKIBHQEK-PWSUYJOCSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 508600   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM508600(2,2-difluoro-8-{2-[(4aR,7aR)- octahydro-6H-pyrrolo...)
Affinity DataKi:  55nMAssay Description:The following table shows representative data for the compounds of the Examples as A2a receptor antagonists as determined by a competition binding as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent