BDBM508643 2,2-difluoro-8-[(2R)-2-(2-methyl- 6,7-dihydropyrazolo[1,5-a]pyrazin- 5(4H)-yl)propyl][1,3]dioxolo[4,5-h] [1,2,4]triazolo[1,5-c]quinazolin-5- amine::US11046714, Example 83

SMILES C[C@H](Cc1nc2c3ccc4OC(F)(F)Oc4c3nc(N)n2n1)N1CCn2nc(C)cc2C1

InChI Key InChIKey=SQIGTHOWPCAUBU-LLVKDONJSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 508643   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM508643(2,2-difluoro-8-[(2R)-2-(2-methyl- 6,7-dihydropyraz...)
Affinity DataKi:  3.80nMAssay Description:The following table shows representative data for the compounds of the Examples as A2a receptor antagonists as determined by a competition binding as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent