BDBM508677 11-[(5-amino-2,2-difluoro[1,3]dioxolo [4,5-h][1,2,4]triazolo[1,5-c]quinazolin- 8-yl)methyl]-3-(trifluoromethyl) azetidin-3-ol::US11046714, Example 113

SMILES Nc1nc2c3OC(F)(F)Oc3ccc2c2nc(CN3CC(O)(C3)C(F)(F)F)nn12

InChI Key InChIKey=NMPGMZHWIHJBBQ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 508677   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM508677(11-[(5-amino-2,2-difluoro[1,3]dioxolo [4,5-h][1,2,...)
Affinity DataKi:  2.80nMAssay Description:The following table shows representative data for the compounds of the Examples as A2a receptor antagonists as determined by a competition binding as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent