BDBM508691 8-({(cyclopropylmethyl)[(4-methyl-1,3- thiazol-2-yl)methyl]amino}methyl)- 2,2-difluoro[1,3]dioxolo[4,5-h][1,2,4] triazolo[1,5-c]quinazolin-5-amine::US11046714, Example 127

SMILES Cc1csc(CN(CC2CC2)Cc2nc3c4ccc5OC(F)(F)Oc5c4nc(N)n3n2)n1

InChI Key InChIKey=WXSHYVOHWRZKNR-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 508691   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM508691(8-({(cyclopropylmethyl)[(4-methyl-1,3- thiazol-2-y...)
Affinity DataKi:  1.40nMAssay Description:The following table shows representative data for the compounds of the Examples as A2a receptor antagonists as determined by a competition binding as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent