BDBM508701 8-[(1S or 1R)-1-(3,3-difluoropiperidin- 1-yl)ethyl]-2,2-difluoro[1,3]dioxolo [4,5-h][1,2,4]triazolo[1,5-c] quinazolin-5-amine (faster eluting b)::US11046714, Example 135

SMILES C[C@@H](N1CCCC(F)(F)C1)c1nc2c3ccc4OC(F)(F)Oc4c3nc(N)n2n1

InChI Key InChIKey=LRNSLGHTGBWWPR-MRVPVSSYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 508701   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM508701(8-[(1S or 1R)-1-(3,3-difluoropiperidin- 1-yl)ethyl...)
Affinity DataKi:  89nMAssay Description:The following table shows representative data for the compounds of the Examples as A2a receptor antagonists as determined by a competition binding as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent