BDBM510051 N-{(1S)-1-Cyano-2-[(3S)-2-oxopyrrolidin-3-yl]ethyl}-N2-(2,6-dichlorobenzoyl)-4-methyl-L- leucinamide (3)::US11351149, Example 3::WO2021250648, Example 3

SMILES CC(C)(C)C[C@H](NC(=O)c1c(Cl)cccc1Cl)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C#N

InChI Key InChIKey=NBUBKDAZNOWKCZ-XEZPLFJOSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 510051   

TargetReplicase polyprotein 1a(2019-nCoV)
Pfizer

US Patent
LigandPNGBDBM510051(N-{(1S)-1-Cyano-2-[(3S)-2-oxopyrrolidin-3-yl]ethyl...)
Affinity DataKi:  439nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandPNGBDBM510051(N-{(1S)-1-Cyano-2-[(3S)-2-oxopyrrolidin-3-yl]ethyl...)
Affinity DataIC50:  439nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandPNGBDBM510051(N-{(1S)-1-Cyano-2-[(3S)-2-oxopyrrolidin-3-yl]ethyl...)
Affinity DataEC50:  6.74E+3nMAssay Description:The ability of compounds to prevent SARS-CoV-2 coronavirus-induced cell death or cytopathic effect can be assessed via cell viability, using an assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed