BDBM510065 N-[(2S)-1-({(1S)-1-Cyano-2-[(3S)-2- oxopyrrolidin-3-yl]ethyl}amino)-4-methyl-1-oxopentan-2-yl]-3-fluoro-4-methoxy-1H- indole-2-carboxamide (17)::US11351149, Example 17::WO2021250648, Example 17

SMILES COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C#N)c(F)c12

InChI Key InChIKey=ZMOZSXJGWLKEFR-DZKIICNBSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 510065   

TargetReplicase polyprotein 1a(2019-nCoV)
Pfizer

US Patent
LigandPNGBDBM510065(N-[(2S)-1-({(1S)-1-Cyano-2-[(3S)-2- oxopyrrolidin-...)
Affinity DataKi:  53nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandPNGBDBM510065(N-[(2S)-1-({(1S)-1-Cyano-2-[(3S)-2- oxopyrrolidin-...)
Affinity DataIC50:  53nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandPNGBDBM510065(N-[(2S)-1-({(1S)-1-Cyano-2-[(3S)-2- oxopyrrolidin-...)
Affinity DataEC50: >333nMAssay Description:The ability of compounds to prevent SARS-CoV-2 coronavirus-induced cell death or cytopathic effect can be assessed via cell viability, using an assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed