BDBM510140 3-Methyl-N-[(4-methylphenyl)acetyl]-L-valyl-(4R)-N-{(1S)-1-cyano-2-[(3S)-2- oxopyrrolidin-3-yl]ethyl}-4-(trifluoromethyl)-L-prolinamide (92)::WO2021250648, Example 92

SMILES Cc1ccc(CC(=O)N[C@H](C(=O)N2C[C@H]3[C@@H]([C@H]2C(=O)N[C@@H](C[C@@H]2CCNC2=O)C#N)C3(C)C)C(C)(C)C)cc1

InChI Key InChIKey=UUOUHARJOCCEAN-ADOUWIFLSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 510140   

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandPNGBDBM510140(3-Methyl-N-[(4-methylphenyl)acetyl]-L-valyl-(4R)-N...)
Affinity DataEC50:  19nMAssay Description:The ability of compounds to prevent SARS-CoV-2 coronavirus-induced cell death or cytopathic effect can be assessed via cell viability, using an assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandPNGBDBM510140(3-Methyl-N-[(4-methylphenyl)acetyl]-L-valyl-(4R)-N...)
Affinity DataIC50:  4nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed