BDBM512578 WO2021219089, INSCoV-517A (1B)

SMILES FC(F)(F)Oc1ccc(N([C@H](C(=O)NC2CCC(F)(F)CC2)c2cncnc2)C(=O)CCl)c(c1)C#N

InChI Key InChIKey=VMGQOZFYMLAXNK-IBGZPJMESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 512578   

TargetReplicase polyprotein 1ab(2019-nCoV)
Insilico Medicine Ip

WIPO
LigandPNGBDBM512578(WO2021219089, INSCoV-517A (1B))
Affinity DataIC50:  3.25E+3nMAssay Description:he C-His6-tagged SARS-CoV-2 M PRO (NC_045512) was cloned, expressed in E. coli and purified by WuXi. The substrate of Dabcyl-KTSAVLQ‖SGFRKME- (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed