BDBM512703 WO2021219089, INSCoV-614A (1B)::WO2021219089, INSCoV-614A (2A)

SMILES F[C@@H](Cl)C(=O)N([C@@H](C(=O)NC1CCC(F)(F)CC1)c1cncnc1)c1ccc(cc1)-c1ccno1

InChI Key InChIKey=AXOSYDUPSLYKSA-WOJBJXKFSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 512703   

TargetReplicase polyprotein 1ab(2019-nCoV)
Insilico Medicine Ip

WIPO
LigandPNGBDBM512703(WO2021219089, INSCoV-614A (1B) | WO2021219089, INS...)
Affinity DataIC50:  180nMAssay Description:he C-His6-tagged SARS-CoV-2 M PRO (NC_045512) was cloned, expressed in E. coli and purified by WuXi. The substrate of Dabcyl-KTSAVLQ‖SGFRKME- (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Insilico Medicine Ip

WIPO
LigandPNGBDBM512703(WO2021219089, INSCoV-614A (1B) | WO2021219089, INS...)
Affinity DataIC50:  5.05E+3nMAssay Description:he C-His6-tagged SARS-CoV-2 M PRO (NC_045512) was cloned, expressed in E. coli and purified by WuXi. The substrate of Dabcyl-KTSAVLQ‖SGFRKME- (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed