BDBM512774 WO2021219089, INCoV-600J (1)::WO2021219089, INCoV-600J (2)

SMILES FC1(F)CCC(CC1)NC(=O)[C@H](N(C(=O)CCl)c1ccc(cc1)-c1ccno1)c1cncnc1

InChI Key InChIKey=WCSKSPGTBVMOKI-OAQYLSRUSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 512774   

TargetReplicase polyprotein 1ab(2019-nCoV)
Insilico Medicine Ip

WIPO
LigandPNGBDBM512774(WO2021219089, INCoV-600J (1) | WO2021219089, INCoV...)
Affinity DataIC50:  63nMAssay Description:he C-His6-tagged SARS-CoV-2 M PRO (NC_045512) was cloned, expressed in E. coli and purified by WuXi. The substrate of Dabcyl-KTSAVLQ‖SGFRKME- (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Insilico Medicine Ip

WIPO
LigandPNGBDBM512774(WO2021219089, INCoV-600J (1) | WO2021219089, INCoV...)
Affinity DataEC50:  1.42E+4nMAssay Description:SARS-CoV-2 was provided by Korea Centers for Disease Control and Prevention (KCDC) . Vero cells were acquired from the ATCC and maintained in the Dul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Insilico Medicine Ip

WIPO
LigandPNGBDBM512774(WO2021219089, INCoV-600J (1) | WO2021219089, INCoV...)
Affinity DataIC50:  530nMAssay Description:he C-His6-tagged SARS-CoV-2 M PRO (NC_045512) was cloned, expressed in E. coli and purified by WuXi. The substrate of Dabcyl-KTSAVLQ‖SGFRKME- (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed