BDBM515 4-hydroxy-3-phenyl-2H-chromen-2-one::Cancer Chemotherapy National Service Center (CCNSC) compound 251152::NSC 251152

SMILES Oc1c(-c2ccccc2)c(=O)oc2ccccc12

InChI Key InChIKey=CBHMYFPBBDCWSY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 515   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes Of Health

LigandPNGBDBM515(4-hydroxy-3-phenyl-2H-chromen-2-one | Cancer Chemo...)
Affinity DataIC50:  4.20E+4nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM515(4-hydroxy-3-phenyl-2H-chromen-2-one | Cancer Chemo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against HIV-1 integraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM515(4-hydroxy-3-phenyl-2H-chromen-2-one | Cancer Chemo...)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM515(4-hydroxy-3-phenyl-2H-chromen-2-one | Cancer Chemo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against HIV-1 integraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed