BDBM516 CHEMBL62658::N-[2,6-bis(propan-2-yl)phenyl]-6-(4-hydroxy-2-oxo-2H-chromen-3-yl)-2,4-dioxo-6-phenylhexanamide::NSC 647086

SMILES CC(C)c1cccc(C(C)C)c1NC(=O)C(=O)CC(=O)CC(c1ccccc1)c1c(O)c2ccccc2oc1=O

InChI Key InChIKey=DJDZPJCHQJIERW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 516   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes Of Health

LigandPNGBDBM516(CHEMBL62658 | N-[2,6-bis(propan-2-yl)phenyl]-6-(4-...)
Affinity DataIC50:  3.10E+4nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM516(CHEMBL62658 | N-[2,6-bis(propan-2-yl)phenyl]-6-(4-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against HIV-1 integraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM516(CHEMBL62658 | N-[2,6-bis(propan-2-yl)phenyl]-6-(4-...)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM516(CHEMBL62658 | N-[2,6-bis(propan-2-yl)phenyl]-6-(4-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against HIV-1 integraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed