BDBM522165 US11161815, Example 21

SMILES COc1ccc(c(n1)S(=O)(=O)Cc1ccc(Cl)cc1)[N+]([O-])=O

InChI Key InChIKey=QHQPQWGEJRXMIV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 522165   

TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
Oblique Therapeutics

US Patent
LigandPNGBDBM522165(US11161815, Example 21)
Affinity DataIC50: >1.00E+5nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
Oblique Therapeutics

US Patent
LigandPNGBDBM522165(US11161815, Example 21)
Affinity DataIC50:  4.35nMAssay Description:Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent