BDBM525231 5-Methyl-N-[rac-(1S)-2-[2-(3-amino-3-oxo-propyl)-2-(2-chloro-2-fluoro-acetyl)hydrazino]-1-(cyclohexylmethyl)-2-oxo-ethyl]isoxazole-3-carboxamide::WO2022043374, Example 74

SMILES Cc1cc(no1)C(=O)N[C@@H](CC1CCCCC1)C(=O)NN(CCC(N)=O)C(=O)C(F)Cl

InChI Key InChIKey=IAYSXJQXETVUDM-KNVGNIICSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 525231   

TargetReplicase polyprotein 1ab(2019-nCoV)
F. Hoffmann-La Roche

WIPO
LigandPNGBDBM525231(5-Methyl-N-[rac-(1S)-2-[2-(3-amino-3-oxo-propyl)-2...)
Affinity DataIC50:  28nMAssay Description:For the SARS-CoV-2 3CLpro assay, 2 μL of 0.02 μM recombinant SARS-CoV-2 3CL protease were mixed with serial dilutions of each c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed