BDBM526278 3-(4-fluoro-5-(methyl((1S,2S)-2- (methylamino)cyclohexyl)amino)-1- oxoisoindolin-2-yl)piperidine-2,6-dione::US11185537, Compound I-163

SMILES CN[C@H]1CCCC[C@@H]1N(C)c1ccc2C(=O)N(Cc2c1F)C1CCC(=O)NC1=O

InChI Key InChIKey=FLQNJRCBMUFCHN-GIIGEWEBSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 526278   

TargetDNA-binding protein Ikaros(Homo sapiens)
Novartis

US Patent
LigandPNGBDBM526278(3-(4-fluoro-5-(methyl((1S,2S)-2- (methylamino)cycl...)
Affinity DataEC50:  570nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM526278(3-(4-fluoro-5-(methyl((1S,2S)-2- (methylamino)cycl...)
Affinity DataEC50:  66nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent