BDBM530433 Racemic 7-Fluoro-6-(5-(1-hydroxyethyl)-1-methyl-1H-1,2,4-triazol-3-yl)-4- isopropyl-2-(o-tolyl)isoquinolin-1(2H)-one.::WO2022070068, Example 5
SMILES CC(C)c1cn(-c2ccccc2C)c(=O)c2cc(F)c(cc12)-c1nc(C(C)O)n(C)n1
InChI Key InChIKey=GFJXHYALUUKZRE-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 530433
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Janssen Biotech
WIPO
Janssen Biotech
WIPO
Affinity DataIC50: 1.10nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair