BDBM530437 7-Fluoro-6-(5-(hydroxymethyl)-1-methyl-1H-1,2,4-triazol-3-yl)-4-isopropyl-2-(o- tolyl)isoquinolin-1(2H)-one.::WO2022070068, Example 9
SMILES CC(C)c1cn(-c2ccccc2C)c(=O)c2cc(F)c(cc12)-c1nc(CO)n(C)n1
InChI Key InChIKey=NJXWXIQUZQHGFW-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 530437
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Janssen Biotech
WIPO
Janssen Biotech
WIPO
Affinity DataIC50: 2.60nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair