BDBM530444 2-(5-Chloro-3-methyl-1H-pyrazol-4-yl)-7-fluoro-6-(2-(2-hydroxypropan-2-yl)-1-methyl-1H-imidazol-4-yl)-4-isopropylisoquinolin-1(2H)-one.::WO2022070068, Example 16
SMILES CC(C)c1cn(-c2c(C)n[nH]c2Cl)c(=O)c2cc(F)c(cc12)-c1cn(C)c(n1)C(C)(C)O
InChI Key InChIKey=YLRTYAFTHNZJRW-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 530444
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Janssen Biotech
WIPO
Janssen Biotech
WIPO
Affinity DataIC50: 0.510nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair