BDBM530467 3-(5-Chloro-3-methyl-1H-pyrazol-4-yl)-7-fluoro-8-(5-(2-hydroxypropan-2-yl)-1- methyl-1H-1,2,4-triazol-3-yl)-1-isopropyl-4H-quinolizin-4-one.::WO2022070071, Example 5

SMILES CC(C)c1cc(-c2c(C)n[nH]c2Cl)c(=O)n2cc(F)c(cc12)-c1nc(n(C)n1)C(C)(C)O

InChI Key InChIKey=BTPMWJMVBJCPSL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 530467   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Janssen Biotech

WIPO
LigandPNGBDBM530467(3-(5-Chloro-3-methyl-1H-pyrazol-4-yl)-7-fluoro-8-(...)
Affinity DataIC50:  2.10nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed