BDBM530469 7-Fluoro-8-(5-(2-hydroxypropan-2-yl)-1-methyl-1H-1,2,4-triazol-3-yl)-1-isopropyl-3-(3-methyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)-4H-quinolizin-4-one.::WO2022070071, Example 7

SMILES CC(C)c1cc(-c2c(C)n[nH]c2C(F)(F)F)c(=O)n2cc(F)c(cc12)-c1nc(n(C)n1)C(C)(C)O

InChI Key InChIKey=UUHLYXDTHMBALL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 530469   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Janssen Biotech

WIPO
LigandPNGBDBM530469(7-Fluoro-8-(5-(2-hydroxypropan-2-yl)-1-methyl-1H-1...)
Affinity DataIC50:  2.51nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed