BDBM530557 WO2022076495, EXAMPLE 3

SMILES C[C@]1(CCS(=O)(=O)C1)NC(=O)c1ccc2n(-c3cccc(OC(F)F)c3)c(=O)n(-c3ccc(F)cc3)c2c1

InChI Key InChIKey=KUGXKMYPDWFZGB-AREMUKBSSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 530557   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck Sharp &Amp

WIPO
LigandPNGBDBM530557(WO2022076495, EXAMPLE 3)
Affinity DataIC50:  2.40nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed