BDBM530590 WO2022076495, EXAMPLE 36

SMILES CC1(CS(=O)(=O)C1)NC(=O)c1cc2n(C3CCOCC3)c(=O)n(-c3cccc(OC(F)F)c3)c2cc1F

InChI Key InChIKey=OSWPMHNADIRNML-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 530590   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck Sharp &Amp

WIPO
LigandPNGBDBM530590(WO2022076495, EXAMPLE 36)
Affinity DataIC50:  19nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed