BDBM530684 WO2022076495, EXAMPLE 115::l-(2-(2,2-difluoroethoxy)-5-fluoropyridin-4-yl)-6-fluoro-3-isopropyl-N-(4-methyl-1,1-dioxidotetrahydro-2H-thiopyran-4-yl)-2-oxo-2,3-dihydro--be1Hnzo[d]imidazole-5-carboxamide

SMILES CC(C)n1c2cc(C(=O)NC3(C)CCS(=O)(=O)CC3)c(F)cc2n(-c2cc(OC(F)F)ncc2F)c1=O

InChI Key InChIKey=JPNGKROFLGMSEE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 530684   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck Sharp &Amp

WIPO
LigandPNGBDBM530684(WO2022076495, EXAMPLE 115 | l-(2-(2,2-difluoroetho...)
Affinity DataIC50:  4.10nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed