BDBM532076 US11208404, Compound 315

SMILES C[F]COc1ccccc1C(=O)Nc1cc(ccc1F)-c1nnc(o1)-c1ccco1

InChI Key InChIKey=UXFDQDPAPMETSB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 532076   

TargetLysocardiolipin acyltransferase 1(Human)
Perenna Pharmaceuticals

US Patent
LigandPNGBDBM532076(US11208404, Compound 315)
Affinity DataIC50: <35nMAssay Description:ALCAT1 enzymatic activity was determined by measuring the conversion of monolysocardiolipin (MLCL) to cardiolipin or lysophosphatidylglycerol (LPG) t...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetLysocardiolipin acyltransferase 1(Human)
Perenna Pharmaceuticals

US Patent
LigandPNGBDBM532076(US11208404, Compound 315)
Affinity DataIC50:  28nMAssay Description:ALCAT1 enzymatic activity was determined by measuring the conversion of monolysocardiolipin (MLCL) to cardiolipin or lysophosphatidylglycerol (LPG) t...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetLysocardiolipin acyltransferase 1(Human)
Perenna Pharmaceuticals

US Patent
LigandPNGBDBM532076(US11208404, Compound 315)
Affinity DataIC50: <35nMAssay Description:ALCAT1 enzymatic activity was determined by measuring the conversion of monolysocardiolipin (MLCL) to cardiolipin or lysophosphatidylglycerol (LPG) t...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent